CAS Number 147732-56-7
INCI Name Palmitoyl Tripeptide-1
Origin
Palmitoyl Tripeptide-1 is created using solid-phase peptide synthesis (SPPS), a process where amino acids are added one by one to build the tripeptide chain. Once the chain is complete, it’s attached to palmitic acid, a fatty acid, to enhance its skin penetration. The final ingredient is then purified to ensure it’s free from impurities.
Purpose
In skincare formulations, Palmitoyl Tripeptide-1 functions as a skin-conditioning agent and humectant, helping to maintain skin hydration, improve texture, and promote a smoother, more supple appearance. It supports the skin’s natural repair processes and helps reduce the appearance of fine lines, making it a valuable component in anti-aging and moisturizing products.
| Feature | Description |
|---|---|
| Name | Palmitoyl Tripeptide-1 |
| Type | Synthetic lipopeptide (signal peptide) |
| Source | Synthetic (laboratory-made; not naturally occurring) |
| pH | 4.0 to 7.0 |
| Color | White to off-white |
| Odor | Odorless |
| Physical State | Solid (usually in powder form) |
| Solubility | Soluble in water and aqueous solutions |
| Concentration | Typically used at 0.5% to 3% in cosmetic products |
Skin Conditioning and Moisturizing Properties
This ingredient is known for its excellent skin-conditioning abilities. It helps soften, smooth, and enhance the texture of the skin by supporting and strengthening the skin’s natural structure. Additionally, Palmitoyl Tripeptide-1 functions as a humectant, attracting moisture from the environment into the skin and maintaining optimal hydration levels. This prevents dryness and dehydration while leaving the skin looking plump, supple, and healthy.
Anti-Aging and Collagen-Boosting Effects
Palmitoyl Tripeptide-1 plays a vital role in anti-aging skincare. It stimulates the production of essential components like collagen types I and III, fibronectin, and hyaluronic acid — all responsible for preserving skin firmness, elasticity, and youthful appearance. This peptide helps minimize the appearance of fine lines and wrinkles over time, promoting a smoother, firmer, and more youthful complexion with consistent use.
Skin Repair and Barrier Support
Beyond its moisturizing and anti-aging effects, this peptide also supports the skin’s natural repair mechanisms. It assists in regenerating damaged or aged skin tissue and contributes to reinforcing the skin’s protective barrier. This strengthens the skin’s resilience against environmental stressors, irritants, and pollutants, making it an ideal ingredient for sensitive, mature, or compromised skin.
Enhanced Penetration and Stability
The attached palmitic acid significantly improves the molecule’s ability to penetrate through the outer layer of the skin and reach deeper levels where it can effectively interact with skin cells. This modification not only enhances absorption but also improves the peptide’s stability in formulations, protecting it from degradation caused by exposure to air, light, or heat. This ensures reliable, long-lasting performance in cosmetic products.
Safety and Compatibility
Palmitoyl Tripeptide-1 is generally well-tolerate by most skin types, including sensitive and mature skin. It is consider safe for regular use when incorporated within recommended concentrations in cosmetic formulations. Moreover, it blends seamlessly with other active ingredients such as hyaluronic acid, niacinamide, and additional peptides, making it highly versatile for a wide range of skincare products like serums, moisturizers, anti-aging creams, and eye treatments.
Storage
Palmitoyl Tripeptide-1 should stored in a cool, dry place, preferably at a temperature between 2°C to 8°C (36°F to 46°F) to preserve its potency and stability. The ingredient should kept in a tightly sealed, light-resistant container to prevent degradation caused by exposure to air, light, and moisture.
Shelf Life
When stored under the recommended conditions in its original, unopened packaging, Palmitoyl Tripeptide-1 typically has a shelf life of 24 months. Once incorporated into a formulation, the final product’s shelf life may vary depending on the overall formulation, preservative system, and packaging.
