INCI name Cetrimonium Chloride
CAS Number 112-02-7
Cetrimonium Chloride is a yellowish liquid commonly found in cosmetic and personal care products, though it can also appear as a solid or paste. Known for its preservative and antiseptic properties, it is frequently used to reduce static in hair. This versatile ingredient is compatible with most other ingredients and is commonly found in products such as shampoos and conditioners.
Purpose
Cetrimonium Chloride is an effective antimicrobial, helping to inhibit the growth of bacteria and other harmful microorganisms in cosmetic and personal care products. Its antistatic properties make it ideal for reducing static in hair, preventing frizz and also flyaways. Additionally, it functions as a preservative, extending the shelf life of products by protecting them from microbial contamination.
Origin
Cetrimonium Chloride can be either natural or synthetic, depending on the manufacturing process. When derived naturally, it comes from vegetable oils. Essentially a quaternary ammonium compound, it is highly effective as a preservative. It typically appears as a yellowish liquid or a waxy solid.

Feature | Description |
---|---|
Name | Cetrimonium Chloride |
Type | Conditioning agent, emulsifier, antimicrobial |
Source | Synthetic |
PH | Acidic |
Concentration | 0.1%–2% |
Physical state | Liquid or solid |
Boiling Point | 475.54°C |
Color | Colorless to pale yellow |
Odor | Mild or characteristic odor |
Solubility | Soluble in water and alcohols, insoluble in oils |
Dual Functionality as Preservative and Antimicrobial Agent
Cetrimonium Chloride serves as both a preservative and an antimicrobial agent, preventing the growth of harmful microorganisms and ensuring that personal care products remain safe and effective over time. This is particularly important for water-based products like shampoos and conditioners, which are more prone to microbial contamination. By inhibiting bacteria and fungi, it helps maintain product stability and hygiene.
Antistatic Properties
A key benefit of Cetrimonium Chloride in hair care products is its antistatic effect, which helps reduce static buildup and prevents frizzy, flyaway hair. This makes it a popular choice for conditioners and styling products, where smoothness and manageability are desired. Additionally, it provides a conditioning effect by minimizing the negative charge on hair fibers, leaving the hair softer and shinier.
Versatility and Compatibility
Cetrimonium Chloride is highly compatible with a variety of other ingredients, making it an essential component in numerous personal care formulations. It blends well with surfactants, oils, and fragrances, ensuring balanced and effective product formulations. It also enhances the emulsification process, helping to blend water and oils in lotions, creams, and conditioners.
Form Availability
This ingredient is available in both liquid and solid (waxy) forms. The liquid form is commonly used in shampoos and aqueous-based products, while the waxy solid form is ideal for richer formulations like deep conditioners and creams. This flexibility allows for a wide range of applications in personal care products.
Plant-Derived and Synthetic Options
Cetrimonium Chloride can be derived naturally from vegetable oils like coconut or palm oil, making it a preferred choice for consumers looking for plant-based and eco-friendly ingredients. The synthetic version provides a consistent and cost-effective alternative, widely used in commercial formulations for its reliability and effectiveness.
Quaternary Ammonium Compound
As a quaternary ammonium compound, Cetrimonium Chloride is highly effective in conditioning and preserving products. Its cationic nature allows it to bond with negatively charged surfaces, such as hair or skin, creating a protective layer that improves moisture retention and texture. This makes it a valuable ingredient in hair care and skincare products, where smoothness, hydration, and longevity are key benefits.
Applications of Cetrimonium Chloride in Skincare and Cosmetics
Hair Care Products
Cetrimonium Chloride is widely used in shampoos, conditioners, hair masks, and leave-in treatments due to its antistatic, conditioning, and detangling properties. It smooths the hair cuticle, reduces frizz, and improves manageability, making it a key ingredient in products designed for damaged or dry hair.
Cleansers and Facial Washes
In facial cleansers and body washes, Cetrimonium Chloride acts as a mild antimicrobial agent and a preservative, helping to prevent bacterial contamination while maintaining product stability. It also contributes to a smooth, non-drying feel on the skin.
Moisturizers and Lotions
As a conditioning agent, Cetrimonium Chloride is sometimes included in lotions, creams, and body butters to enhance skin softness and spreadability. It helps create a smooth texture and improves the absorption of moisturizing ingredients.
Makeup and Cosmetic Formulations
In foundations, primers, and setting sprays, Cetrimonium Chloride can improve texture and help products adhere better to the skin. Its antistatic properties can also reduce powder clumping in pressed or loose powders.
Deodorants and Antiperspirants
Due to its antimicrobial properties, Cetrimonium Chloride is used in deodorants and antiperspirants to help prevent odor-causing bacteria while maintaining product stability.
Sunscreens and After-Sun Care
In sunscreens and after-sun gels, Cetrimonium Chloride helps emulsify and stabilize formulations, ensuring even application and long-lasting effectiveness.
Wipes and Cleansing Pads
It is often included in makeup remover wipes, baby wipes, and facial cleansing pads as a preservative and conditioning agent, ensuring that the product remains effective and free from bacterial contamination.